The 1st Workshop on Modeling Nature: from Nano to Macro (MNAT2018) will be organized at the University of Granada, Spain, within the Scientific Unit of Excellence MNat. The Global dimension of this workshop is extended for researchers and students. During the 1-day workshop the cutting edge in evolutionary biology and global ecology, Bio-Nanotechnology modelling, tumor dynamics and targeted therapies and their interdisciplinary modelling making use of calculus of Variations,